Detalhe da pesquisa
1.
In Vitro and in Vivo Study of a Photostable Quinone Compound with Enhanced Therapeutic Efficacy against Chagas Disease.
Chem Pharm Bull (Tokyo)
; 72(4): 389-392, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38644164
2.
Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis.
Antimicrob Agents Chemother
; 67(3): e0142822, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840588
3.
Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum.
Proc Natl Acad Sci U S A
; 116(17): 8269-8274, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30952781
4.
Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I.
J Biol Chem
; 295(8): 2449-2463, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953326
5.
Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection.
Antimicrob Agents Chemother
; 65(10): e0041821, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339272
6.
5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro.
Biochem Biophys Res Commun
; 545: 203-207, 2021 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571909
7.
In vivo efficacy of combination therapy with albendazole and atovaquone against primary hydatid cysts in mice.
Eur J Clin Microbiol Infect Dis
; 40(9): 1815-1820, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-33770336
8.
Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase.
Int J Mol Sci
; 22(13)2021 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34281290
9.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
FASEB J
; 33(11): 13002-13013, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525300
10.
Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region.
Malar J
; 19(1): 439, 2020 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256739
11.
Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target.
Biochim Biophys Acta Bioenerg
; 1859(3): 191-200, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269266
12.
Monotherapy with a novel intervenolin derivative, AS-1934, is an effective treatment for Helicobacter pylori infection.
Helicobacter
; 23(2): e12470, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29488678
13.
Dihydroorotate Dehydrogenase as a Target for the Development of Novel Helicobacter pylori-Specific Antimicrobials.
Chem Pharm Bull (Tokyo)
; 66(3): 239-242, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29491257
14.
Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei.
Protein Expr Purif
; 138: 56-62, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28642005
15.
Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Biochim Biophys Acta Gen Subj
; 1861(11 Pt A): 2830-2842, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778484
16.
Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase.
Malar J
; 16(1): 247, 2017 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28606087
17.
Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase.
Bioorg Med Chem
; 25(4): 1465-1470, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28118956
18.
Structure of the trypanosome cyanide-insensitive alternative oxidase.
Proc Natl Acad Sci U S A
; 110(12): 4580-5, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23487766
19.
Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis.
Biochim Biophys Acta
; 1837(7): 1219-25, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24530866
20.
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol Microbiol
; 94(6): 1315-29, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25315291